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Rabies is one of the most lethal viruses on earth, with almost 60,000 people dying of this terrible disease every year. Almost half of these deaths are children, mostly in Africa and Asia. However, rabies is preventable and there is a global goal of achieving zero human dog-mediated rabies deaths by 2030.

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Asia and Africa are the main regions affected by rabies in dogs, whilst wildlife may be affected in many parts of the world. Find out where the latest reported outbreaks are with this map.

Key Facts
Clinical Signs

Clinical signs in dogs with rabies include aggression/unusual behaviour, excessive salivation, and choking/gagging. In animals and humans the disease is 100% fatal once clinical signs/symptoms occur. As such rabies has one of the highest mortality rates of any disease.


Prevention is the key to controlling and eliminating rabies, with dog vaccination the main tool. People that are bitten by a dog should take appropriate action to wash and clean the wound and seek medical attention.


The disease is 100% preventable. In recent decades countries across Latin America and the Caribbean have made strides towards rabies elimination, and in November 2019, Mexico proved that human canine-mediated deaths can be eliminated when it became the first country in the world to obtain WHO validation for no human rabies deaths. Mexico achieved this by having a national rabies strategy based on mass dog vaccination, raising public awareness, and post-exposure prophylaxis. The cooperation of human and animal health sectors is important in achieving rabies elimination, and rabies is a good example of how a One Health approach can be very effective.

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Focus On… Building of a Network of Rabies “Champions”
Rabies is a lethal encephalitis due to a lyssavirus mainly transmitted to humans by the bite or scratches of terrestrial carnivores (principally domestic dogs).
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